Singapore Society of Oncology - 6th Annual Scientific Meeting

This year the Singapore Society of Oncology’s 6th annual scientific meeting (originally BASCO 2021) will be held virtually. Illumina will be hosting a 30 min industry workshop and a virtual booth as a gold sponsor. The workshop is a 30 min session in the Gastrointestinal Track, attend our session to listen to Dr Daniel Croagh - HPB (Hepato-Pancreatico-Biliary) Surgeon, Lecturer in Surgery from Monash Health share his team’s interim results from the endoscopic ultrasound Molecular Evaluation of Pancreatic Cancer (EU ME PC) Trial.

Industry Workshop

Track: Gastrointestinal Track

Date: 10 July 2021 (Sat)

Time: 11:15- 11:45 (Singapore Time)

Speaker: Dr. Daniel Croagh

Title: HPB (Hepato-Pancreatico-Biliary) Surgeon, Lecturer in Surgery, Monash Health

Talk Title:
Interim Results from the Endoscopic Ultrasound Molecular Evaluation of Pancreatic Cancer (EU ME PC) Trial

Abstract:

The EU ME PC trial is a multi-center study examining the utility of Endoscopic Ultrasound FNA to provide tissue for comprehensive molecular profiling of pancreatic cancer for patients with metastatic, locally advanced or recurrent pancreatic cancer. The trial incorporates the use of either an additional fresh frozen biopsy banked at the time of diagnostic EUS or the use of archival formalin fixed paraffin embedded tissue. DNA and RNA are extracted from these tissues and if adequate are sequenced using the TSO500 gene panel. RNA is also used to assess a novel diagnostic gene signature that we have developed and this is compared to the results of the TSO500 gene signature to further validate the utility of this diagnostic signature and its potential as a tool for assessing the adequacy of biopsy samples prior to NGS. The results of the TSO500 gene panels are reviewed at a molecular tumour board and fed back to treating clinicians. The trial has been open for just over 12 months and recruited 55 patients. The preliminary results are presented here.