Each reagent kit contains all the required consumables for a single flow cell sequencing run. For sequencing runs requiring custom primers, Custom-Primer Buffer is available for purchase (sold separately). Spare accessories including air filters, wash flow cells, wash reagent cartridges, and sample tubes are also available for purchase (sold separately).
NovaSeq X Series Reagent Kits combine the power of XLEAP-SBS chemistry with flexible, efficient, and sustainable workflows to enable transformational science at scale.
165 Gb to 16 Tb of highly accurate and reliable data per run to support variable batch sizes‡
100-, 200-, and 300-cycle kits to support a wide range of applications—from spatial transcriptomics and single-cell studies to exomes and genomes
Up to 8 lanes per flow cell to simplify pooling and indexing strategies and support multiomic approaches
A 4-fold reduction in library input† to maximize precious samples
> 50% reduction in plastic* and > 90% reduction in packaging* to reduce waste and maximize storage space
The Debut of XLEAP-SBS Chemistry
NovaSeq X Series Reagent Kits are powered by XLEAP-SBS chemistry: a faster, more accurate, and more robust update to traditional sequencing by synthesis (SBS) chemistry. The stability of XLEAP-SBS reagents also supports consistent, reliable data generation for results you can trust.
Flexible Configurations to Support Multiple Applications
With up to 8 independent lanes per flow cell, NovaSeq X Series flow cells streamline operations by enabling automatically loading of up to 8 separate library pools per flow cell—without the need for an accessory kit. Increased sample partitioning also simplifies indexing strategies and better enables multiomic approaches.
Sustainability and Simplicity In One
NovaSeq X Series Reagent Kits pair the streamlined, load-and-go convenience of NovaSeq 6000 Reagent Kits with industry-leading sustainability improvements. NovaSeq X Series Reagent Kits arrive at room temperature, with no dry ice and no ice packs, for less waste* and a streamlined unpacking experience. Additionally, the cartridges are constructed with more recyclable plastics,* including a biopolymer derived from sugar cane. Following completion of the sequencing run, cartridges can be disassembled for easier recycling and disposal.
*Compared to NovaSeq 6000 Reagent Kits †Compared to NovaSeq 6000 onboard workflow ‡NovaSeq X Series 25B Reagent Kits available 2H 2023