NextSeq 1000 & NextSeq 2000 Innovation & Expertise

Gain momentum with the most trusted benchtop sequencers

Confidently bring NGS to your lab with proven technology and support

Research scientists discussing sequencing results.

Innovations that empower researchers across the globe

Illumina is committed to upholding a proven track record of solutions that empower researchers to advance and accelerate their sequencing. That’s why we have invested billions into our research and development and infrastructure to ensure we can equip you with what you need to succeed.

When you partner with Illumina, you’ll get more than just leading-edge technology–you become part of a community with like-minded goals.

Inspiring bold discoveries with global expertise

Our pursuit of innovation continues to inspire scientists to join our growing genomics community, and our proven performance has contributed to Illumina being cited more than any other sequencing company.


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Find community and get comprehensive support at every step

Illumina provides a wide range of global, in-language support including remote technical support 24/5, onsite training, instrument qualification and customized onboarding solutions. Because of this, 9 out of 10 customers find it easy to do business with our team.

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Get comprehensive support
  • 96% customer satisfaction
  • 97% of calls answered in <30 seconds
  • <1 day mean time to repair
  • 2-day average FSE response time
Connect with fellow innovators

Become a part of a community advancing science together by leading the latest advancements in research and sharing best practices.

Explore Illumina collaborations

Illumina partnerships are expanding access to NGS, pioneering new applications and technologies, providing funding for innovative startups, and more.

Advance your research with streamlined, sustainable benchtop sequencing

Streamline your workflows

Lessen time-to-insight with simple workflows from library prep to data analysis.

Sequence sustainably

Reduce your environmental footprint with sustainable solutions.

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Join thousands of researchers who have simplified their sequencing

NextSeq 1000 and NextSeq 2000 systems are flexible and scalable, empowering scientists to explore current and emerging applications like single cell, whole exome, and RNA sequencing. These easy-to-use systems feature an improved user experience with simplified run setup, minimal touchpoints, and flexible informatics solutions, including onboard DRAGEN. The breakthrough system design uses integrated reagent cartridges to minimize waste volume and improve recyclability.

Discover NextSeq 1000 and NextSeq 2000 Systems

See how Illumina benchtop sequencers can transform your lab—today

Dr. Hoa Giang of Gene Solutions was one of the first scientists globally to bring the Illumina NextSeq 2000 System into the lab to help scale and transform their research. See how his team easily transitioned to the NextSeq 2000 System, and how the flexibility of flow cell choice, ease-of-use, and sustainable cartridge features are advancing their projects.

Dr. Hoa Giang of Gene Solutions

Make your most ambitious research a reality with NextSeq 1000 and NextSeq 2000 innovations

  • <10 minute interface setup with local, cloud, or hybrid run setup
  • Up to 11 different flow cell configurations, with more to come, supporting a wide range of applications
  • Compatibility with a broad range of library prep solutions
  • Dry instrument design and integrated single cartridge for streamlined maintenance, optimized instrument up-time, and minimal waste
NextSeq 2000 timeline of advancements from 2020-2024

See NextSeq 1000 and NextSeq 2000 Systems applications

Empowering even more discoveries: XLEAP-SBS chemistry coming H1 2024

Achieve the next level of scale, cost efficiencies, and sequencing capabilities on NextSeq 1000 and NextSeq 2000 Sequencing Systems. Coming in the first half of 2024, XLEAP-SBS Chemistry on existing kits (P1/P2/P3) and a new P4 flow cell will offer 1.7B reads and allow for 500Gb of genomic data.

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"Using the NextSeq 2000 instrument has put our laboratory [into] a completely different league. The higher throughput and faster turnaround time made it possible for us to generate our results and reports much faster and [in] a more comprehensive way."

NextSeq 1000 and NextSeq 2000 are the only benchtop sequencers with integrated, onboard analysis—at no extra cost

With the NextSeq 1000 and NextSeq 2000 onboard DRAGEN software, labs can reduce the need for additional computing infrastructure and bioinformatics resources. And with decreased data analysis complexity, researchers can efficiently find key insights in large data sets.

3x reduction in touchpoints for analysis data with BaseSpace

6x faster on-board secondary analysis than Local Run Manager

10+ pipelines that support a wide variety of experiment types

80% less energy for a more sustainable workplace

Up to 5x decrease in data footprint possible with ORA Compression

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Illumina for your benchtop sequencer

Get in touch to find out how Illumina benchtop sequencing can support your research efforts.

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Hear from the scientific community

Managing throughput demands to support critical programs

In this video, learn about the robustness of the NextSeq 2000 System and how it was able to support Dr Tomas Szemes’ team from Comenius University Science Park, in Slovakia, to double their previous sequencing efforts.

Enriching sequencing workflows with NextSeq 1000 and NextSeq 2000 Systems

Hear from researchers who have used the NextSeq 1000 and NextSeq 2000 Systems for genomic surveillance, CRISPR screening, single-cell RNA Seq, and more, in this introductory video.

Expanding applications and utility with longer reads and extended informatics

Gain a deeper perspective on the flexibility, streamlined workflow, flow cell configurations, informatics, and future innovations of the NextSeq 1000 and NextSeq 2000 Systems in this webinar.

  1. Internal data on file. Illumina, Inc., 2022