Next-generation sequencing (NGS) can provide comprehensive coverage of genes with known associations to inherited heart conditions.
Inherited cardiac conditions are associated with many different genes, with most causative gene variants being unique familial variants1, and therefore, seen infrequently.2 Additionally, panels currently used in clinical research can miss causal gene variants implicated in inherited cardiac conditions (ICCs).
Single-gene assays or assays with smaller gene sets lead to time-consuming and expensive iterative testing for ICCs. NGS of multiple cardiac genes simultaneously results in maximum efficiency not found in other modalities.
From library prep, arrays, and sequencing to informatics, Illumina next-generation solutions empower researchers and clinicians across the globe to find the answers they seek.
We’re here with all the resources you need to accelerate progress. In addition to onsite training, ongoing support, and phone consults, we offer webinars and courses around the world.
We offer a comprehensive workflow with coverage of cardiac gene variants with known associations to inherited heart conditions. The TruSight Cardio Sequencing Kit is fully supported on the MiSeq and NextSeq 500/550 Sequencing Systems.
Sequence data are exported as .vcf files and imported easily into the VariantStudio software for analysis.
Access more focused applications such as targeted gene sequencing, metagenomics, small genome sequencing, targeted gene expression, and amplicon sequencing.
Perform NGS and microarray scanning all on one system.
A comprehensive, cost-effective solution for identifying cardiac gene variants implicated in inherited cardiac conditions (ICCs).
Phosphorus uses the DRAGEN Bio-IT Platform to perform genomics data analysis onsite and at an accessible price point.Read Article