In this video, you will see how researchers used mouse forebrain organoids and PIPseq single-cell RNA sequencing from Illumina to uncover how early neural networks first emerge. The study reveals distinct activity patterns and cell compositions that shape developing circuits in the absence of external input. Watch to learn how this approach is helping define the intrinsic rules that guide early brain wiring. Learn more about PIPseq single-cell RNA sequencing: https://www.illumina.com/techniques/sequencing/rna-sequencing/ultra-low-input-single-cell-rna-seq/pip-seq-chemistry.html Learn more about Illumina Single Cell 3' RNA Prep: https://www.illumina.com/products/by-type/sequencing-kits/library-prep-kits/single-cell-rna-prep.html Subscribe to the Illumina video channel http://www.youtube.com/subscription_center?add_user=IlluminaInc A global genomics leader, Illumina provides comprehensive next-generation sequencing solutions to the research, clinical, and applied markets. Through collaborative innovation, Illumina is fueling groundbreaking advancements in oncology, reproductive health, genetic disease, microbiology, agriculture, forensic science, and beyond. View customer spotlight videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajfheLzgbI4S7xBn7IDbt79 View Illumina webinars https://www.youtube.com/playlist?list=PLKRu7cmBQlahpXlnrrXlQw9itVJ8yHwUZ View Illumina support videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajbm2KGsICWb-JOnusJfYvM LinkedIn: https://www.linkedin.com/company/illumina X: https://x.com/illumina Instagram: https://www.instagram.com/illuminainc/ Facebook: https://www.facebook.com/illuminainc TikTok: https://www.tiktok.com/@illuminainc