Illumina and GenoScreen Deeplex® Myc-TB Combo Kit

A targeted NGS-based assay for sequencing mycobacterium, M. tuberculosis complex (MTBC) strains, and antimicrobial resistance markers.

< 48 hr from sample to completed analysis

Assay time

9 pg DNA

Input quantity

See full details in the specifications table

Kits are not available in all countries/regions. Contact your sales representative for availability.

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Overview
Applications
Documentation

Overview

The Illumina and GenoScreen Deeplex® Myc-TB Combo Kit is a targeted next-generation sequencing panel for the identification of Mycobacterium tuberculosis complex (MTBC) strains, mycobacterial species identification, genotyping, and prediction of drug resistance mutations of MTBC strains. Data analysis is included via a cloud-based Deeplex® software web application with results visualization. Two kit options are available based on which library prep is desired.

Identification of resistance mutations to 15 anti-tuberculosis drugs
Genotyping and spoligotyping of MTBC strains to determine lineage and sublineage of strains present in a sample
Identification of >140 mycobacterial species and detection of co-infections with distinct species
Total turnaround time less than 48 hours directly from sputum with no need to perform culture

Combo kits contain either Illumina DNA Prep (IDP) or Nextera XT library prep, plus the Deeplex® Myc-TB multiplex panel, indexes, and bioinformatic analysis. Choose the SKU that includes the library prep you prefer.

Specifications

Assay time	< 48 hr from sample to completed analysis
Description	PCR panel, library prep, indexes and bioinformatics analysis for identification of mycobacterium tuberculosis and mutations associated with antimicrobial resistance from sputum samples or mycobacterial cultures. Access to detailed interactive cloud-based software included in kit.
Input quantity	9 pg DNA
Instruments	MiSeq System, iSeq 100 System, NextSeq 550 System, MiSeqDx in Research Mode, MiniSeq System, NextSeq 550Dx in Research Mode, NextSeq 500 System, MiSeq i100 Plus System, MiSeq i100 System
Mechanism of action	Multiplex PCR
Method	Targeted DNA sequencing
Multiplexing	Varies by instrument
Nucleic acid type	DNA
Number of amplicons	24
Species category	Bacteria
Technology	Sequencing

Applications

Example workflow

Prep

Illumina and GenoScreen Deeplex® Myc-TB Combo Kit

Sequence

Analyze

Deeplex® Myc-TB Web App

Related applications and methods

Tuberculosis sequencing

Next-generation sequencing is advancing the detection, characterization, and surveillance of drug-resistant tuberculosis strains.

Antimicrobial resistance detection

Next-generation sequencing offers high-throughput capabilities to identify genomic changes associated with antimicrobial resistance.

Public health surveillance

Genomics can advance public health and wellness by detecting and characterizing new, emerging, and circulating pathogens.

Documentation

Product literature

Deeplex Myc-TB Example Report
Product information sheet PDF < 1 MB

Deeplex Myc-TB Technical Note
Technical note PDF 4 MB

Support documentation

GenoScreen Deeplex Myc–TB User Manual Documentation

Illumina and Genoscreen Deeplex® Myc-TB Combo Kit with IDP Library Prep, 48 sample

20099512

Illumina and Genoscreen Deeplex Myc-TB Combo Kit is a multiplex PCR panel used with NGS for M. tuberculosis and associated drug resistance markers. It includes the PCR panel, Illumina DNA Prep (IDP) library prep, indexes, and software access.

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Illumina and Genoscreen Deeplex Myc-TB Combo Kit with Nextera XT library prep, 48 sample

20090205

Illumina and Genoscreen Deeplex Myc-TB Combo Kit is a multiplex PCR panel used with NGS for M. tuberculosis and associated drug resistance markers. It includes the PCR panel, Nextera XT library prep, indexes, and software access.

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Illumina and GenoScreen Deeplex® Myc-TB Combo Kit

< 48 hr from sample to completed analysis

9 pg DNA

Overview

Specifications

Applications

Example workflow

Prep

Sequence

Analyze

Related applications and methods

Documentation

Product literature

Support documentation

Selection summary

Summary

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For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

Illumina and GenoScreen Deeplex® Myc-TB Combo Kit

< 48 hr from sample to completed analysis

9 pg DNA

Overview

Specifications

Applications

Example workflow

Prep

Sequence

Analyze

Related applications and methods

Documentation

Product literature

Support documentation

Selection summary

Frequently purchased

NovaSeq X Series ordering