The NovaSeq 6000 Sequencing System is designed to adapt to your needs. This robust, scalable system has been adopted by leading research centers and featured in countless publications. Impactful discoveries are within reach.
Contact an Illumina RepresentativeSo many ways to sequence. Scale up and down with a tunable output of up to 6 Tb and 20B single reads in < 2 days.
Accelerate your science with reliable sequencing breadth and depth for every project.
Do what you want. Mix and match flow cell types, run one or two flow cells at a time, choose between multiple read lengths, workflows, and more.
Dr. Carolyn Hogg and Professor Kathy Belov are researchers from the University of Sydney, Australia who are using whole genome sequencing of rare and endangered species with aims to provide conservation plans for the species ongoing survival.
View VideoThe NovaSeq 6000 system offers deep and broad coverage through advanced applications for a comprehensive view of the genome. Unlock a full spectrum of genetic variation and biological function with high-throughput sequencing.
See All ApplicationsManage Workflow
Manage your workflow seamlessly with BaseSpace Clarity LIMS or your existing LIMS system.
Prepare Libraries
Prepare libraries with a broad range of high-performance library preparation kits.
Sequence
Generate sequences with ready-to-use reagents featuring proven Illumina sequencing by synthesis chemistry.
Analyze Data
Leverage the Illumina DRAGEN Bio-IT Platform or BaseSpace Sequence Hub for accurate, rapid secondary analysis.
Interpret Results
Interpret results, get insights, and drive discovery with BaseSpace Variant Interpreter, and TruSight Software Suite.
NovaSeq 6000 System | NovaSeq X Series | |
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Key Features: |
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Run Time: | ~13 hr - ~44 hr | ~13 hr - ~48 hr |
Maximum Output: | 6 Tb | 16 Tb (for NovaSeq X Plus system) |
Maximum Reads per Run: | 20 billion single-end reads; 40 billion paired-end reads | 52 billion single-end reads; 104 billion paired-end reads (for NovaSeq X Plus system) |
Maximum Read Length: | 2 x 250 bp | 2 x 150 bp |
Key Applications: | Whole-genome sequencing Whole-exome sequencing Whole-transcriptome sequencing |
Whole-genome sequencing Whole-exome sequencing Whole-transcriptome sequencing |
DRAGEN Data Analysis Offerings: | (on-premise or cloud) DRAGEN Germline DRAGEN Enrichment DRAGEN Somatic DRAGEN RNA |
(onboard) DRAGEN Germline DRAGEN Enrichment DRAGEN RNA DRAGEN Illumina Complete Long Read WGS |
Featured Products: | NovaSeq 6000 Reagent Kits NovaSeq XP Workflow Illumina RNA Prep with Enrichment Illumina DNA PCR-Free Prep Illumina Complete Long Read Prep, Human |
Novaseq X Series Reagent Kits Illumina DNA PCR-Free Prep Illumina DNA Prep with Enrichment Illumina Stranded Total RNA Prep |
Probe deeper into a single sample for insights or process more samples to improve statistical signficance.
Perform transformative science with access to multiple emerging high-throughput omics applications.
Long-read sequencing enables the sequencing of much longer DNA fragments than traditional short-read sequencing methods.
New kits feature updated reagent formulations with 2x longer shelf life and improved sequencing costs to help power your most impactful studies.
The NovaSeq 6000 Xp workflow enables labs to load libraries directly into each lane of a NovaSeq 6000 system flow cell, without additional instrumentation.
Achieve rapid, targeted interrogation of an expansive number of target genes with exceptional capture efficiency and coverage uniformity.
A high-performing, fast, and integrated workflow for sensitive applications such as human whole-genome sequencing.
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See what’s possible with the proven NovaSeq 6000 system and NGS technology
See All StoriesRady Children’s Institute for Genomic Medicine is using the DNA PCR-Free Prep kit for NovaSeq 6000 to make a potentially record-breaking time-to-diagnosis for children with rare genetic disorders
Read MoreCole Trapnell, PhD is transforming the world of biology by making bioinformatics tools available to all
Read MoreOmniSeq, Inc. scaled up to process a large number of both tissue and blood plasma samples every week, batching from 16 to 192 samples in a single run on the NovaSeq 6000
Read MoreGenomics England’s human genome initiative (GenOMICC) has launched a study aimed at uncovering genetic factors in susceptibility to COVID-19
Read MoreThe DRAGEN platform enables GeneDx to scale to whole-genome analysis and identify variants with precision
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