Targeted genotyping approaches provide a cost-effective alternative to whole-genome methods, when genome-wide genotyping is not practical or necessary. Targeted genotyping conserves lab resources and enables deeper coverage of rare variants. Illumina offers microarray and next-generation sequencing (NGS) genotyping solutions to target the exome or focus on specific genes of interest.
Targeted arrays allow you to genotype specific sets of targeted single nucleotide polymorphisms (SNPs), and focus research efforts on biologically meaningful variants. Microarrays with targeted content also enable greater throughput for screening high sample volumes. Illumina offers a variety of disease-specific and population-specific array solutions for targeted genotyping.
Find and compare targeted human genotyping arrays with this simple tool.Find the Right Array Find the Right Array
Develop genotyping arrays with custom markers to target any genomic regions or variants of interest, for any species.Explore Custom Genotyping
Genotyping by sequencing (GBS) offers efficiency for discovering, validating, and screening genetic variants using a highly targeted approach. Targeted GBS approaches can complement arrays by detecting novel variants in specific genome regions, and provide a lower cost alternative for some genotyping applications. Deep sequencing of targeted regions also helps characterize rare variants. Learn more about GBS.
Identify germline mutations that predispose individuals to cancer using targeted microarrays and next-generation sequencing. Learn more about cancer germline mutation studies.
High-throughput microarrays help labs identify common genetic variations among large cohorts for population-scale genotyping studies. Learn more about high through-put genotyping.
After a variant is identified and associated with disease, targeted array and sequencing methods can help determine how a variant affects disease biology. Learn more about disease variant validation.
Uncovering genetic variation in animals and plants can help inform breeding decisions, and may reveal mutations responsible for disease or parasite susceptibility. Learn more about plant and animal genotyping.