Illumina at
ASHG 2026

From the accuracy and accessibility of short-read sequencing to long-range insights traditionally limited to long-read platforms - TruPath Genome is sequencing reimagined. The ultra-simple research workflow unlocks insights in challenging genomic regions, structural variants, and phased variant calls across the human genome.

From genomic variants to methylation status: The Illumina 5-base solution enables direct detection of five DNA bases—adenine (A), thymine (T), cytosine (C), guanine (G), and 5-methylcytosine (5mC) at cytosine-guanine dinucleotide (CpG) sites—in a single sequencing workflow. The Illumina 5-base solution supports high sequence alignment rates and information-rich data. The optimized workflow integrates one library prep, one sequencing run, and one analysis pipeline to deliver dual omic insights for your research without added assay complexity.

From tissue section to whole-transcriptome insight: Illumina StrataMap Spatial solution delivers unbiased whole‑transcriptome spatial profiling at true single-cell resolution—combining high sensitivity, large tissue coverage, and seamless integration with Illumina sequencing and analysis to reveal tissue biology for your research in its native context.

From expression signals to cellular context: Illumina single cell opens doors to new discoveries by enabling sensitive detection of transcripts from fragile cells and complex tissues. All with a simple vortexer-based workflow with no need for costly microfluidics.

From protein quantification to functional insight: Measure over 9500 proteins across ~10 orders of magnitude, capturing high‑ and low‑abundance signals to support biomarker discovery and pathway‑level insight. Exceptional specificity and sensitivity enables detection of subtle biological signals, reducing required sample size, cost, and study complexity while maintaining statistical confidence for your research.