The 5th Annual Conference of the Korean Society of Animal Genetic Breeding in 2021 will be held from 1- 2 July 2021. The theme for this year is precision breeding research: from genomic selection to discovery of new phenotypes. Illumina is proud to be a sponsor for this annual event, join our industry workshop on 1 July.
Industry Workshop
| Date | July 1st |
|---|---|
| Time | 4:40 PM- 5:10 PM (KST) |
| Speaker | Dr. Ruidong Xiang Research Fellow, Computational Biology Faculty of Veterinary and Agricultural Sciences The University of Melbourne, Australia |
| Title | Integrating Functional Information into Genome-wide Mapping and Prediction of Cattle Traits' |
| Abstract | Understanding how DNA mutations change phenotypes is a central research topic in biology. Also, genome-wide DNA markers can be used to predict phenotype which allows better treatment of patients and genomic selection in agriculture. Genome-wide association studies (GWAS) prioritize genetic loci associated with complex traits. However, due to linkage disequilibrium (LD), it has been difficult for GWAS to identify causal mutations for complex traits. Also, while genomic prediction has revolutionized the breeding industry, its accuracy is far from being perfect. Recent efforts in functional genomics present opportunities to prioritize potentially causal mutations independent of LD. In this talk, Ruidong will present the results and methodologies regarding the incorporation of functional and evolutionary information into the genome-wide analysis of cattle complex traits. Their results show that using functional and evolutionary information not only improves the mapping of causal variants, mapped variants can also be integrated into a customized SNP chip to improve genomic prediction of cattle traits worldwide. |